S. pombe pac1+, whose overexpression inhibits sexual development, encodes a ribonuclease III-like RNase.

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Purification and characterization of the Pac1 ribonuclease of Schizosaccharomyces pombe.

The pac1+ gene of the fission yeast Schizosaccharomyces pombe is essential for viability and its overexpression induces sterility and suppresses mutations in the pat1+ and snm1+ genes. The pac1+ gene encodes a protein that is structurally similar to RNase III from Escherichia coli, but its normal function is unknown. We report here the purification and characterization of the Pac1 protein after...

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ژورنال

عنوان ژورنال: The EMBO Journal

سال: 1991

ISSN: 0261-4189

DOI: 10.1002/j.1460-2075.1991.tb07939.x